Xolair is approved down to the age of 12 years old for the treatment of Chronic Idiopathic Urticaria (Chronic Hives). So if taking antihistamines is not providing complete relief or the side effects of antihistamines is too much to handle then this may the relief you are looking for. It’s a once a month injection under your skin (on the back of your arms). It’s a unique treatment given by your allergist.